AstraZeneca Pharmaceuticals LP Associate Principal Scientist – Lung Regeneration, IMED RIA Sweden in Mölndal, Sweden

Respiratory is one of AstraZeneca’s main therapy areas. Our aim is to transform asthma and COPD treatment through inhaled combinations at the core of care, biologics for the unmet needs of specific patient populations, and scientific advancements in disease modification.

From a research perspective we work to understand, treat, modify and ultimately cure respiratory disease with an emphasis on four diseases with significant unmet medical need; asthma, COPD, Idiopathic Pulmonary Fibrosis (IPF) and Chronic Cough. Recently, we reshaped our strategic focus into three mechanistic and complimentary areas in chronic lung disease: Lung Immunity, Lung Epithelium and Lung Regeneration.

To further strengthen our expertise and capacity in each of these strategic research areas we are currently recruiting world-class scientists. Do you want to join our team?

Our Respiratory research is mainly carried out at the vibrant AstraZeneca Research site in Gothenburg, Sweden. However, collaboration is a way of life for us. Extensive collaboration with our AstraZeneca colleagues in Cambridge UK, the MedImmune research units in Gaithersburg and Cambridge, as well as numerous academic institutions and partners around the globe gives us access to a worldwide network of expertise and innovation.

Our external collaborators expand both academic and biotech organisations including Imperial College London, Pieris, Bicycle Therapeutics, Ethris and many more. We aim to be flexible, responsive, open and honest and look for people, companies and investigators who share our collaborative spirit and high scientific standards.

Main Duties and Responsibilities

The remit of the RIA Lung Regeneration Department is to generate in vitro, in vivo and ex vivo Biology data to further our understanding of the potential in lung regeneration in chronic lung disease and support the biology ranging from the target idea stage up until Phase 3 investment decision.

To be successful in executing our bold ambitions, we need your skills in lung cell isolation, multi-cell complex culture systems, stem cell culture and genetic manipulation. As Associate Principal Scientist in Lung Regeneration you have a good understanding of the range of procedures relating to bioanalysis/bioscience. You will get the opportunity to design and conduct laboratory projects and experiments, develop methods, generate, interpret and report scientific data. If you are competent in trouble shooting and theory and inspired by the possibilities of science to make a difference and ready to discover what you can do – join us.

Accountabilities and responsibilities:

  • Executes drug discovery research experiments independently by applying the techniques of molecular and cellular biology

  • Communicates results to team members and is involved in the interpretation of data

  • Supports the team and works collaboratively with project managers to ensure the efficient relay of information and forward translation of data

  • Maintains a well-developed understanding of approaches to drug discovery and applies a broader functional knowledge of the procedures used by diverse project groups to support the department where needed

  • Assesses and reports data, with little or no guidance, in a clear and concise manner, with a clear understanding of its implications within the overall context of drug discovery

  • Provides technical instruction to the team and allocates administrative work where possible

  • Shares relevant external published papers with peers

  • Communicates and shares information between distinct projects within the bioscience function and across other functions

  • Coaching less experienced scientists to develop their skills and maximize their potential.

  • Will contribute to publishing papers in internationally recognised journals and will present work internally and externally

  • Will participate in and contribute to local discipline review groups

  • May lead one or more aspects of the scientific discipline within their team

  • Will have a good working knowledge of all relevant company policies - ensure GLS compliance, compliance with corporate code of conduct and adherence to best SHE practice for self and others - and national regulations, and ensure that industry standards are applied to working for self and others within the discipline team.

  • Will have a broad understanding of own function, and will have a clear understanding of overall AZ R&D objectives. Will be regarded as a source of scientific knowledge inside the department.

  • Contributes to a science-driven and entrepreneurial organization hungry for new ideas, innovative ways of working and continuous learning

  • Positive can-do attitude, with respect for the individuals with different skillset and knowledge, eager to learn in each interaction.

  • Collaborate closely with other teams to drive efficiency and take advantage of knowledge and experiences.

Essential Requirements

  • PhD or BSc/MSc with relevant academic and/or industrial experience  

  • At least 5 years of experience in the pharmaceutical industry or equivalent qualification

  • Background in drug discovery and development in the pharmaceutical industry

  • Good understanding of the range of procedures relating to respiratory diseases

  • Extensive experience in fibroblast biology, mesenchymal stem cell biology and/or epithelial cell biology and relation to tissue fibrosis and regeneration research

  • Experience in flow cytometric and/or flow cytometric-based cell sorting

  • An understanding of respiratory diseases including COPD and IPF

  • An understanding of progression of drug targets through to the clinical setting

  • Strong scientific drive, good networking and communication skills and delivery focus is required

  • Established scientific publications record

  • A good understanding of the drug development process, from lead identification through clinical development

  • Ability to work productively in a matrix team environment and excellent collaborative skills

  • Excellent written and oral communicational skills

  • Good networking and communication skills and a strong delivery focus

If you are interested, apply now!

For more information about the position please contact Lynne Murray, lynne.murray1@astrazeneca.com

Welcome with your application no later than August 9th, 2018.

For more information about life in Gothenburg visit www.movetogothenburg.com

AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law. AstraZeneca only employs individuals with the right to work in the country/ies where the role is advertised.