AstraZeneca Pharmaceuticals LP Senior Expert Peptide Chemistry in Gothenburg, Sweden

Are you an expert in peptide chemistry? Are you aiming for a role where you will provide scientific leadership within your discipline? Would you like to apply your expertise in a company that are following the science and turn ideas into life changing medicines? Then you might be the one we are looking for!

AstraZeneca is now looking to recruit a Principal Scientist with expertise in Peptide Chemistry to join the Medicinal Chemistry Department within the Cardiovascular, Renal and Metabolism (CVRM) therapeutic area at AstraZeneca in Gothenburg, Sweden

The Innovative Medicines (IMED) Biotech Unit of CVRM is one of AstraZeneca´s core therapy areas. We push the boundaries of science to deliver life-changing medicines to patients suffering from Heart Failure, Diabetes or Chronic Kidney Disease. To realize our ambitions, we stay agnostic to molecular modality. We drive our pipeline and the areas of scientific leadership to a large extent in collaborations with world experts which provides you as a scientist with the unique opportunity to access the most advanced knowledge and opportunities to stay at the fore-front of science. The Medicinal Chemistry Department within the CVRM IMED is a critical player in the discovery and design of our drug molecules as well as in identifying and validating novel biological targets.

Main Duties and Responsibilities

This is a senior scientific role within the Medicinal Chemistry department. You will be an authority in peptide medicinal chemistry and are expected to develop and lead the science in the field, including linear, cyclic and stapled peptides and peptide conjugates. You will drive impact on multiple projects across the portfolio in all phases from target selection to drug candidate selection. There will be expectations on lab contribution and being part of the team delivery of peptides. The role holder will also provide discipline based scientific leadership and represent the department and AstraZeneca at interdisciplinary meetings internally as well as externally.

Key Deliverables:

  • Expand and further build our core peptide chemistry capability

  • Responsible, together with the Medicinal Chemistry Leadership Team, for clear and compelling scientific strategy for peptide chemistry in both medicinal and synthetic chemistry

  • Instrumental in delivering a portfolio of peptide projects and peptide-drug-conjugate projects for e.g. targeted drug delivery

  • May lead collaborations and secure new collaborations in the area

Essential Requirements

This role requires a PhD degree in a relevant scientific discipline, ideally with 10 or more years of post-doctoral research experience in drug discovery, preferentially from an industrial setting. You are recognised internationally within the field of peptide chemistry applied to drug discovery as evidenced by your external disclosures and publication record. You are also expected to have:

  • Expert knowledge with proven track record of peptide design and synthesis

  • Ability to identify, develop and apply new technologies and ways of working within peptide chemistry

  • Very good influencing skills in order to build capability and implement improvements

  • Very good knowledge of related disciplines including Drug Metabolism, Pharmacokinetics, Safety, Bioscience, Patent, Pharmaceutical Development

  • Very good written and verbal communication skills, including presentation to senior leaders

  • Excellent awareness of recent literature within field of expertise

  • Strong ability to work collaboratively and build relationships

  • Demonstrated scientific leadership through publishing in peer reviewed journals or presentations at internal/external conferences.

  • We are looking for a highly self-motivated and scientifically driven individual with expertise in peptide chemistry that is capable of receiving and analyzing input from multiple disciplines.

If you are interested, apply now!

For more information about the position please contact Dr. Anders Dahlén, Team Leader New Modalities Chemistry, CVRM IMED;

Welcome with your application no later than May 31, 2018.

AstraZeneca is a global, innovation-driven biopharmaceutical company that focuses on the discovery, development and commercialization of prescription medicines for some of the world’s most serious diseases. In addition to being one of the world's leading pharmaceutical companies, AstraZeneca is proud to provide a unique workplace culture that inspires innovation and cross-boundary collaboration. Within this environment employees are empowered to express diverse perspectives, and are made to feel valued, energized and rewarded for their ideas and creativity.

AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law. AstraZeneca only employs individuals with the right to work in the country/ies where the role is advertised.